Prognostic value of the lactate–albumin difference for predicting in-hospital mortality in critically ill patients with sepsis

Objective: To evaluate the prognostic performance of lactate–albumin difference (LAD), maximum lactate levels, and Sequential Organ Failure Assessment (SOFA) score taken on first day in critically ill patients with sepsis, in-hospital mortality 90-day survival.Patients Methods: Data from Medical Information Mart for Intensive Care III (MIMIC III) version 1.4 were evaluated retrospectively. The data adult sepsis diagnosed according to Third International Consensus Definitions Sepsis Septic Shock (Sepsis-3) criteria recorded. effectiveness all diagnostic modalities admission was analyzed predict survival. Results: In-hospital 20.3% among 2270 included this study. area below receiver operating characteristic curve (AUC) value LAD higher than predicting (AUC, 0.691; 95% confidence interval [CI], 0.663–0.718; p< 0.01, AUC, 0.675; CI, 0.646–0.703; respectively), AUC SOFA highest 0.716; 0.663–0.718). optimal cutoff 0.7. Conclusion: In addition its easy simple calculability relative SOFA, superior levels survival sepsis.